mAb PK, TMDD, ADC modeling, FcRn binding, and allometric scaling
Target-mediated drug disposition model for monoclonal antibodies
Scale monoclonal antibody PK parameters across species using allometry
Estimate monoclonal antibody half-life from FcRn binding and IgG subclass
Estimate subcutaneous bioavailability relative to IV for biologics
Visualize antibody-drug conjugate PK: total antibody, conjugated antibody, and free payload profiles with DAR effects
Estimate mAb half-life from FcRn binding affinity (KD at pH 6.0), isoelectric point, and molecular weight