Therapeutic Index Calculator

Calculator

Calculate Therapeutic Index (TD50/ED50) and Certain Safety Factor (TD1/ED99). Assess drug safety margins. Free, instant, with AI interpretation.

Enter values and click Calculate to see results

For educational and research purposes only. Not intended as medical advice. Always verify calculations independently and consult qualified healthcare professionals. See our Terms of Service for full details.

Educational Content

Reviewed by

PharmKit Clinical Team

PharmD, BCPS — Clinical Pharmacology

You might also need

Exposure Margin Calculator

Calculate AUC and Cmax exposure margins from anima

Phenytoin Dosing (Winter-Tozer)

Correct phenytoin levels for low albumin and renal

DDI Risk Assessment (FDA)

FDA static model R1/R2/R3 for CYP inhibition and i

First-in-Human Dose Calculator

Calculate maximum recommended starting dose (MRSD)

Concentration-QTc Visualizer

Perform concentration-QTc analysis with linear reg

Exposure-Response Explorer

Fit logistic regression to binary exposure-respons